acetyl-S-ACP:malonate ACP transferase EC#: 2.3.1.187; 凯望编码 (ChemWhat Code): 1376995
| 英文名 | acetyl-S-ACP:malonate ACP transferase |
| Example Structure | ![]() |
| 别名 | acetyl-S-ACP:malonate ACP transferase, acetyl-S-ACP:malonate ACP-SH transferase, acetyl-S-acyl carrier protein:malonate acyl carrier protein-SH transferase, acetyl-S-acyl-carrier protein:malonate acyl-carrier-protein-transferase, MadA, malonate/acetyl-CoA transferase, malonate:ACP transferase, malonyl-CoA:ACP transacylase, MdcA, MdcH |
| EC Number | 2.3.1.187 |
| CAS编号 | |
| Comments | This is the first step in the catalysis of malonate decarboxylation and involves the exchange of an acetyl thioester residue bound to the activated acyl-carrier protein (ACP) subunit of the malonate decarboxylase complex for a malonyl thioester residue [2]. This enzyme forms the ¦Á subunit of the multienzyme complexes biotin-independent malonate decarboxylase (EC 4.1.1.88) and biotin-dependent malonate decarboxylase (EC 7.2.4.4). The enzyme can also use acetyl-CoA as a substrate but more slowly [4]. |
| Cofactor | |
| History | |
| Reactions | An acetyl-[acyl-carrier protein] + malonate = a malonyl-[acyl-carrier protein] + acetate. |
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