| 英文名 |
acetylene hydratase |
| Example Structure |
 |
| 别名 |
(E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, AH, HMBPP reductase, ispH, More, tungsten-dependent acetylene hydratase |
| EC Number |
4.2.1.112 |
| CAS编号 |
|
| Comments |
This is a non-redox-active enzyme that contains two molybdopterin guanine dinucleotide (MGD) cofactors, a tungsten centre and a cubane type [4Fe-4S] cluster [2]. The tungsten centre binds a water molecule that is activated by an adjacent aspartate residue, enabling it to attack acetylene bound in a distinct hydrophobic pocket [2]. Ethylene cannot act as a substrate [1]. |
| Cofactor |
W cation
Mo-bis(molybdopterin guanine dinucleotide)
iron-sulfur |
| History |
|
| Reactions |
Acetaldehyde = acetylene + H(2)O. |
