| 英文名 |
acireductone synthase |
| Example Structure |
 |
| 别名 |
E-1, enolase-phosphatase, Enoph1, MASA |
| EC Number |
3.1.3.77 |
| CAS编号 |
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| Comments |
This bifunctional enzyme first enolizes the substrate to form the intermediate 2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate, which is then dephosphorylated to form the acireductone 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one [2]. The acireductone represents a branch point in the methione-salvage pathway as it is used in the formation of formate, CO and 3-(methylsulfanyl)propanoate by EC?1.13.11.53?[acireductone dioxygenase (Ni2+-requiring)] and of formate and 4-(methylsulfanyl)-2-oxobutanoate either by a spontaneous reaction under aerobic conditions or by EC?1.13.11.54?{acireductone dioxygenase [iron(II)-requiring]} [1,2]. |
| Cofactor |
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| History |
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| Reactions |
5-(methylthio)-2,3-dioxopentyl phosphate + H(2)O = 1,2-dihydroxy-5- (methylthio)pent-1-en-3-one + phosphate. |
