ADAMTS-4 endopeptidase EC#: 3.4.24.82; 凯望编码 (ChemWhat Code): 1381091
| 英文名 | ADAMTS-4 endopeptidase |
| Example Structure |  |
| 别名 | a disintegrin and metalloprotease with thrombospondin motifs-4, a disintegrin and metalloproteinase with thrombospondin motif, a disintegrin and metalloproteinase with thrombospondin motifs-4, a disintegrin and metalloproteinase with thrombospondin-1-like motifs, ADAMTS 4, ADAMTS-1, ADAMTS-4, ADAMTS-4 [a disintegrin and metalloproteinase with thrombospondin motifs-4], ADAMTS-4-2, ADAMTS4, agg-1, aggrecanase, aggrecanase 1, aggrecanase-1, disintegrin and metalloproteinase with thrombospondin motif 4, TS-4 |
| EC Number | 3.4.24.82 |
| CAS编号 | |
| Comments | In peptidase family?M12. Thought to be biologically significant for the degradation of the aggrecan component of cartilage matrix. |
| Cofactor | Zn2+ |
| History | |
| Reactions | Glutamyl endopeptidase; bonds cleaved include 370-Thr-Glu-Gly-Glu-|-Ala- Arg-Gly-Ser-377 in the interglobular domain of mammalian aggrecan. |
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