| 英文名 |
alcohol dehydrogenase (azurin) |
| Example Structure |
 |
| 别名 |
ADH IIB, ADH IIG, QH-ADH, quinohaemoprotein alcohol dehydrogenase, quinohemoprotein alcohol dehydrogenase |
| EC Number |
1.1.9.1 |
| CAS编号 |
|
| Comments |
A soluble, periplasmic PQQ-containing quinohemoprotein. Also contains a single heme c. Occurs in Comamonas and Pseudomonas. Does not require an amine activator. Oxidizes a wide range of primary and secondary alcohols, and also aldehydes and large substrates such as sterols; methanol is not a substrate. Usually assayed with phenazine methosulfate or ferricyanide. Like all other quinoprotein alcohol dehydrogenases it has an 8-bladed ‘propeller’ structure, a calcium ion bound to the PQQ in the active site and an unusual disulfide ring structure in close proximity to the PQQ. |
| Cofactor |
pyrroloquinoline quinone;heme |
| History |
|
| Reactions |
A primary alcohol + azurin = an aldehyde + reduced azurin. |
