| Comments |
Along with EC?3.5.2.15?(cyanuric acid amidohydrolase) and EC?3.5.1.84?(biuret amidohydrolase), this enzyme forms part of the cyanuric-acid metabolism pathway, which degrades?s-triazide herbicides, such as atrazine [2-chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5-triazine], in bacteria. The yeast enzyme (but not that from green algae) also catalyses the reaction of EC?6.3.4.6?urea carboxylase, thus bringing about the hydrolysis of urea to CO2?and NH3?in the presence of ATP and bicarbonate. The enzyme from?Pseudomonas?sp. strain ADP has a narrow substrate specificity, being unable to use the structurally analogous compounds urea, hydroxyurea or methylcarbamate as substrate [6]. |
