aminopeptidase S EC#: 3.4.11.24; 凯望编码 (ChemWhat Code): 1380302
| 英文名 | aminopeptidase S |
| Example Structure |  |
| 别名 | |
| EC Number | 3.4.11.24 |
| CAS编号 | |
| Comments | Aminopeptidases are associated with many biological functions, including protein maturation, protein degradation, cell-cycle control and hormone-level regulation [3,4]. This enzyme contains two zinc molecules in its active site and is activated by Ca2+?[4]. In the presence of Ca2+, the best substrates are Leu-Phe, Leu-Ser, Leu-pNA (aminoacyl-p-nitroanilide), Phe-Phe-Phe and Phe-Phe [3]. Peptides with proline in the P1′ position are not substrates [3]. Belongs in peptidase family?M28. |
| Cofactor | Zn2+ |
| History | |
| Reactions | Release of an N-terminal amino acid with a preference for large hydrophobic amino-terminus residues. |
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