| 英文名 |
archaeosine synthase |
| Example Structure |
 |
| 别名 |
ARChaeosine synthase, ArcS, ATP-independent amidinotransferase, MJ1022, SSO0016, TgtA2, tRNA-guanine transglycosylase |
| EC Number |
2.6.1.97 |
| CAS编号 |
|
| Comments |
In Euryarchaeota the reaction is catalysed by ArcS [1,2]. In Crenarchaeota, which do not have an ArcS homologue, the reaction is catalysed either by a homologue of EC?6.3.4.20, 7-cyano-7-deazaguanine synthase that includes a glutaminase domain (cf. EC?3.5.1.2), or by a homologue of EC?1.7.1.13,?preQ1?synthase [2]. The enzyme from the Euryarchaeon?Methanocaldococcus jannaschii?can also use arginine and ammonium as amino donors. |
| Cofactor |
|
| History |
|
| Reactions |
L-glutamine + 7-cyano-7-carbaguanine(15) in tRNA + H(2)O = L-glutamate + archaeine(15) in tRNA. |