| 英文名 |
arginine-pyruvate transaminase |
| Example Structure |
 |
| 别名 |
arginine/lysine:pyruvate transaminase, arginine:pyruvate transaminase, aruF mutant, AruH, ATASE, L-arginine inducible arginine:pyruvate transaminase, L-arginine:pyruvate transaminase |
| EC Number |
2.6.1.84 |
| CAS编号 |
|
| Comments |
A pyridoxal-phosphate protein. While?L-arginine is the best substrate, the enzyme exhibits broad substrate specificity, with?L-lysine,?L-methionine,?L-leucine,?L-ornithine and?L-glutamine also able to act as substrates, but more slowly. Pyruvate cannot be replaced by 2-oxoglutarate as amino-group acceptor. This is the first catalytic enzyme of the arginine transaminase pathway for?L-arginine utilization in?Pseudomonas aeruginosa. This pathway is only used when the major route of arginine catabolism, i.e. the arginine succinyltransferase pathway, is blocked. |
| Cofactor |
pyridoxal 5′-phosphate |
| History |
|
| Reactions |
L-arginine + pyruvate = 5-guanidino-2-oxopentanoate + L-alanine. |
