| 英文名 |
arsenate reductase (thioredoxin) |
| Example Structure |
 |
| 别名 |
ARS, ArsC, ArsC1, ArsC1′, ArsC3, arsenate reductase, Bs_ArsC, pI258 arsenate reductase, plasmid pI258 arsenate reductase, Sa_ArsC, Strop634, thioredoxin-arsenate reductase complex, thioredoxin-coupled arsenate reductase, Trx-coupled arsenate reductase |
| EC Number |
1.20.4.4 |
| CAS编号 |
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| Comments |
The enzyme, characterized in bacteria of the Firmicutes phylum, is specific for thioredoxin [1]. It has no activity with glutaredoxin [cf. EC 1.20.4.1, arsenate reductase (glutaredoxin)]. Although the arsenite formed is more toxic than arsenate, it can be extruded from some bacteria by EC 7.3.2.7, arsenite-transporting ATPase; in other organisms, arsenite can be methylated by EC 2.1.1.137, arsenite methyltransferase, in a pathway that produces non-toxic organoarsenical compounds. The enzyme also has the activity of EC 3.1.3.48, protein-tyrosine-phosphatase [3]. |
| Cofactor |
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| History |
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| Reactions |
Arsenate + thioredoxin = arsenite + thioredoxin disulfide + H(2)O. |
