| 英文名 |
aspartate/glutamate leucyltransferase |
| Example Structure |
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| 别名 |
bacterial protein transferase, BPT, LD,E-transferase, Leu-conjugating aa-transferase, leucylD,E-transferase |
| EC Number |
2.3.2.29 |
| CAS编号 |
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| Comments |
The enzyme participates in the N-end rule protein degradation pathway in certain bacteria, by attaching the primary destabilizing residue L-leucine to the N-termini of proteins that have an N-terminal L-aspartate or L-glutamate residue. Once modified, the proteins are recognized by EC 3.4.21.92, the ClpAP/ClpS endopeptidase system. cf. EC 2.3.2.6, lysine/arginine leucyltransferase, and EC 2.3.2.8, arginyltransferase. |
| Cofactor |
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| History |
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| Reactions |
(1) L-leucyl-tRNA(Leu) + N-terminal L-glutamyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-glutamyl-[protein]. (2) L-leucyl-tRNA(Leu) + N-terminal L-aspartyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-aspartyl-[protein]. |
