| 英文名 |
aurachin C monooxygenase/isomerase |
| Example Structure |
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| 别名 |
auaG, aurachin C monooxygenase, MimA, MimABCD, Msmeg_1971 |
| EC Number |
1.14.13.222 |
| CAS编号 |
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| Comments |
The aurachin C monooxygenase from the bacterium Stigmatella aurantiaca accepts both NADH and NADPH as cofactor, but has a preference for NADH. It catalyses the initial steps in the conversion of aurachin C to aurachin B. The FAD-dependent monooxygenase catalyses the epoxidation of the C2-C3 double bond of aurachin C, which is followed by a semipinacol rearrangement, causing migration of the farnesyl group from C3 to C4. |
| Cofactor |
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| History |
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| Reactions |
Aurachin C + NAD(P)H + O(2) = 4-hydroxy-2-methyl-3-oxo-4-((2E,6E)- farnesyl)-3,4-dihydroquinoline-1-oxide + NAD(P)(+) + H(2)O. |
