bile acid CoA-transferase EC#: 2.8.3.25; 凯望编码 (ChemWhat Code): 1379160

英文名 bile acid CoA-transferase
Example Structure Example Structure of bile acid CoA-transferase EC#: 2.8.3.25
别名 baiF, baiK, bile acid coenzyme A transferase
EC Number 2.8.3.25
CAS编号
Comments The enzyme, characterized from the gut bacterium?Clostridium scindens, catalyses the last step in bile acid 7¦Á-dehydroxylation, the removal of the CoA moiety from the products. By using a transferase rather than hydrolase, the bacteria conserve the thioester bond energy, saving ATP molecules. The enzyme has a broad substrate specificity and can use multiple acceptors, including allocholate, ursodeoxycholate, and ¦Â-muricholate. Formerly EC?3.1.2.26.
Cofactor
History
Reactions (1) Lithocholoyl-CoA + cholate = lithocholate + choloyl-CoA. (2) Deoxycholoyl-CoA + cholate = deoxycholate + choloyl-CoA.

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