| 英文名 |
caffeoyl-CoA reductase |
| Example Structure |
 |
| 别名 |
caffeoyl-CoA reductase-Etf complex, electron-bifurcating caffeoyl-CoA reductase, hydrocaffeoyl-CoA:NAD+, ferredoxin oxidoreductase |
| EC Number |
1.3.1.108 |
| CAS编号 |
|
| Comments |
The enzyme, characterized from the bacterium Acetobacterium woodii, contains two [4Fe-4S] clusters and FAD. The enzyme couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant. It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction. It also reduces 4-coumaroyl-CoA and feruloyl-CoA. |
| Cofactor |
iron-sulfur;FAD |
| History |
|
| Reactions |
3-(3,4-dihydroxyphenyl)propanoyl-CoA + 2 NAD(+) + 2 reduced ferredoxin [iron-sulfur] cluster = (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl-CoA + 2 Nadh + 2 oxidized ferredoxin [iron-sulfur] cluster. |
