carboxylate reductase (NADP+) EC#: 1.2.1.30; 凯望编码 (ChemWhat Code): 1373775

英文名 carboxylate reductase (NADP+)
Example Structure Example Structure of carboxylate reductase (NADP+) EC#: 1.2.1.30
别名 aromatic acid reductase, aryl-aldehyde dehydrogenase (NADP+)
EC Number 1.2.1.30
CAS编号 9074-94-6
Comments The enzyme contains an adenylation domain, a phosphopantetheinyl binding domain, and a reductase domain, and requires activation by attachment of a phosphopantetheinyl group. The enzyme activates its substrate to an adenylate form, followed by a transfer to the phosphopantetheinyl binding domain. The resulting thioester is subsequently transferred to the reductase domain, where it is reduced to an aldehyde and released.
Cofactor
History
Reactions An aromatic aldehyde + NADP(+) + Amp + diphosphate + H(2)O = an aromatic acid + Nadph + atp.

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