| 英文名 |
carminomycin 4-O-methyltransferase |
| Example Structure |
 |
| 别名 |
anthracycline 4-O-methyltransferase, COMT, DauK, DnrK |
| EC Number |
2.1.1.292 |
| CAS编号 |
|
| Comments |
The enzymes from the Gram-positive bacteria Streptomyces sp. C5 and Streptomyces peucetius are involved in the biosynthesis of the anthracycline daunorubicin. In vitro the enzyme from Streptomyces sp. C5 also catalyses the 4-O-methylation of 13-dihydrocarminomycin, rhodomycin D and 10-carboxy-13-deoxycarminomycin [3]. |
| Cofactor |
|
| History |
|
| Reactions |
S-adenosyl-L-methionine + carminomycin = S-adenosyl-L-homocysteine + daunorubicin. |
