| 英文名 |
carotenoid isomerooxygenase |
| Example Structure |
 |
| 别名 |
carotenoid cleavage oxygenase, CCO, NinaB, ppsir_15490, Rv0654, sala_1698, SIR-1 |
| EC Number |
1.13.11.65 |
| CAS编号 |
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| Comments |
The enzyme, characterized from the moth Galleria mellonella and the fruit fly Drosophila melanogaster, is involved in the synthesis of retinal from dietary caroteoids in insects. The enzyme accepts different all-trans carotenoids, including ¦Â-carotene, ¦Á-carotene and lutein, and catalyses the symmetrical cleavage of the carotenoid and the simultaneous isomerization of only one of the products to a cis configuration. When the substrate is hydroxylated only in one side (as in cryptoxanthin), the enzyme preferentially isomerizes the hydroxylated part of the molecule. Formerly EC 1.14.13.164. |
| Cofactor |
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| History |
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| Reactions |
Zeaxanthin + O(2) = (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3- hydroxyretinal. |
