| 英文名 |
cypemycin N-terminal methyltransferase |
| Example Structure |
 |
| 别名 |
alpha-N-methyltransferase, CypM, S-adenosyl methionine-dependent methyltransferase |
| EC Number |
2.1.1.301 |
| CAS编号 |
|
| Comments |
The enzyme, isolated from the bacterium Streptomyces sp. OH-4156, can methylate a variety of oligopeptides, cyclic peptides such as nisin and haloduracin, and the ¦Å-amino group of lysine [2]. Cypemycin is a peptide antibiotic, a member of the linaridins, a class of posttranslationally modified ribosomally synthesized peptides. |
| Cofactor |
|
| History |
|
| Reactions |
2 S-adenosyl-L-methionine + N-terminal L-alanine-[cypemycin] = 2 S-adenosyl-L-homocysteine + N-terminal N,N-dimethyl-L-alanine- [cypemycin]. |
