| 英文名 |
D-2-hydroxyglutarate dehydrogenase |
| Example Structure |
 |
| 别名 |
2-hydroxyglutarate dehydrogenase, AtD-2HGDH, D-2-HGA, D2-hydroxyglutarate dehydrogenase, D2HGDH |
| EC Number |
1.1.99.39 |
| CAS编号 |
|
| Comments |
Contains FAD. The enzyme has no activity with NAD+ or NADP+, and was assayed in vitro using artificial electron acceptors. It has lower activity with (R)-lactate, (R)-2-hydroxybutyrate and meso-tartrate, and no activity with the (S) isomers. The mammalian enzyme is stimulated by Zn2+, Co2+ and Mn2+. |
| Cofactor |
FAD |
| History |
|
| Reactions |
(R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor. |
