| 英文名 |
D-inositol-3-phosphate glycosyltransferase |
| Example Structure |
 |
| 别名 |
CgMshA, MshA, MSMEG0924, mycothiol glycosyltransferases |
| EC Number |
2.4.1.250 |
| CAS编号 |
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| Comments |
The enzyme, which belongs to the GT-B fold superfamily, catalyses the first dedicated reaction in the biosynthesis of mycothiol [1]. The substrate was initially believed to be inositol, but eventually shown to be D-myo-inositol 3-phosphate [2]. A substantial conformational change occurs upon UDP binding, which generates the binding site for D-myo-inositol 3-phosphate [3]. |
| Cofactor |
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| History |
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| Reactions |
UDP-N-acetyl-D-glucosamine + 1D-myo-inositol 3-phosphate = Udp + 1-O- (2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol 3-phosphate. |
