| 英文名 |
deacetoxycephalosporin-C hydroxylase |
| Example Structure |
 |
| 别名 |
cefF, Cephalosporin biosynthesis expandase/hydroxylase, DACS, DAOC hydroxylase, DAOC synthase, DAOC/DAC synthase, DAOCS, deacetoxycephalosporin C hydroxylase, deacetoxycephalosporin C synthase, deacetylcephalosporin C synthase |
| EC Number |
1.14.11.26 |
| CAS编号 |
|
| Comments |
Requires iron(II). The enzyme can also use 3-exomethylenecephalosporin C as a substrate to form deacetoxycephalosporin C, although more slowly [2]. In Acremonium chrysogenum, the enzyme forms part of a bifunctional protein along with EC 1.14.20.1, deactoxycephalosporin-C synthase. It is a separate enzyme in Streptomyces clavuligerus. |
| Cofactor |
Fe2+ |
| History |
|
| Reactions |
Deacetoxycephalosporin C + 2-oxoglutarate + O(2) = deacetylcephalosporin C + succinate + CO(2). |
