| 英文名 |
demethylmenaquinone methyltransferase |
| Example Structure |
 |
| 别名 |
2-heptaprenyl-1,4-naphthoquinone methyltransferase, DMK methyltransferase, Dmkt1, DmtH protein, menaquinone biosynthesis methyltransferase, UbiE |
| EC Number |
2.1.1.163 |
| CAS编号 |
|
| Comments |
The enzyme catalyses the last step in menaquinone biosynthesis. It is able to accept substrates with varying polyprenyl side chain length (the chain length is determined by polyprenyl diphosphate synthase) [1]. The enzyme from Escherichia coli also catalyses the conversion of 2-methoxy-6-octaprenyl-1,4-benzoquinone to 5-methoxy-2-methyl-3-octaprenyl-1,4-benzoquinone during the biosynthesis of ubiquinone [4]. The enzyme probably acts on menaquinol rather than menaquinone. |
| Cofactor |
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| History |
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| Reactions |
A demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + S-adenosyl-L-homocysteine. |
