| 英文名 |
demethylrebeccamycin-D-glucose O-methyltransferase |
| Example Structure |
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| 别名 |
rebeccamycin MT, rebeccamycin O-methyltransferase, RebM, RebM. |
| EC Number |
2.1.1.164 |
| CAS编号 |
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| Comments |
Catalyses the last step in the biosynthesis of rebeccamycin, an indolocarbazole alkaloid produced by the bacterium Lechevalieria aerocolonigenes. The enzyme is able to use a wide variety substrates, tolerating variation on the imide heterocycle, deoxygenation of the sugar moiety, and even indolocarbazole glycoside anomers [1]. The enzyme is a member of the general acid/base-dependent O-methyltransferase family [2]. |
| Cofactor |
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| History |
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| Reactions |
4′-demethylrebeccamycin + S-adenosyl-L-methionine = rebeccamycin + S-adenosyl-L-homocysteine. |
