Dextran CAS#: 9004-54-0; 凯望编码 (ChemWhat Code): 137072
Identification
| 英文名 | Dextran |
| IUPAC Name | 2,3,4,5-tetrahydroxy-6-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal |
| 分子结构 |  |
| CAS编号 | 9004-54-0 |
| EINECS Number | 232-677-5 |
| MDL Number | MFCD00132771 |
| 别名 | DEXTRAN 9004-54-0 Dextran 40 Macrodex 2,3,4,5-tetrahydroxy-6-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal Hexopyranosyl-(1->6)hexopyranosyl-(1->6)hexose Dextran 70 6-O-(6-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)-D-glucose 13382-86-0 Medium Dextran T40 Dextran-500kd SEPHADEX G-50 Dextran (MW 70000) Dextran (Mw 150000) SCHEMBL12557981 DTXSID00864149 FZWBNHMXJMCXLU-UHFFFAOYSA-N (2R,3S,4R,5R)-2,3,4,5-tetrahydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal BCP13568 AKOS015915689 D1448 D1449 DEX 500; Detrax 40; Dextranen; Dextraven G72625 2,3,4,5-tetrahydroxy-6-((3,4,5-trihydroxy-6-(((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal |
| 分子式 | C18H32O16 |
| 分子量 | 504.4 |
| InChI | InChI=1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2 |
| InChI Key | FZWBNHMXJMCXLU-UHFFFAOYSA-N |
| Isomeric SMILES | C(C1C(C(C(C(O1)OCC2C(C(C(C(O2)OCC(C(C(C(C=O)O)O)O)O)O)O)O)O)O)O)O |
| Patent Information | ||
| Patent ID | Title | Publication Date |
| US5104787 | Method for apparatus for a defined serumfree medical solution useful for corneal preservation | 1992 |
| EP516901 | Method and apparatus of a serumfree medical solution | 1992 |
| US2009/47336 | NOVEL FORMULATION OF DEHYDRATED LIPID VESICLES FOR CONTROLLED RELEASE OF ACTIVE PHARMACEUTICAL INGREDIENT VIA INHALATION | 2009 |
| US2012/148542 | MACHINE PERFUSION WITH COMPLEMENT INHIBITORS | 2012 |
| US5849884 | Macromolecular microparticles and methods of production and use | 1998 |
Physical Data
| Appearance | White or light yellow delicate powder |
| Description (Association (MCS)) | Solvent (Association (MCS)) | Temperature (Association (MCS)), °C | Partner (Association (MCS)) |
| Adsorption isotherm | various solvent(s), H2O | 20 | 4-Fluo zeolite Y |
| Further physical properties of the complex | Azinc tetrakis(4-carboxyphenyl)porphyrin | ||
| UV/VIS spectrum of the complex | H2O | 25 | |
| Association with compound | H2O | 10 – 80 | bovine serum γ-globulin |
Spectra
| Description (NMR Spectroscopy) | Nucleus (NMR Spectroscopy) | Solvents (NMR Spectroscopy) | Temperature (NMR Spectroscopy), °C | Frequency (NMR Spectroscopy), MHz |
| Spectrum | 1H | |||
| Spectrum | 1H | water-d2 | ||
| Chemical shifts, Spectrum | 1H | dimethylsulfoxide-d6 | 20 | |
| Chemical shifts | 1H | dimethylsulfoxide-d6 | ||
| Spectrum | 13C | |||
| Chemical shifts, Spectrum | 1H | water-d2 | ||
| Spectrum | 1H | 600 |
| Description (IR Spectroscopy) | Solvent (IR Spectroscopy) |
| Bands, Spectrum | |
| Intensity of IR bands, ATR (attenuated total reflectance), Bands, Spectrum | |
| Spectrum | |
| Bands, Spectrum | potassium bromide |
| Description (UV/VIS Spectroscopy) |
| Spectrum |
| Absorption maxima |
Route of Synthesis (ROS)
| Conditions | Yield |
| With dicyclohexyl-carbodiimide In dimethyl sulfoxide for 24h; Heating / reflux; Experimental Procedure EXAMPLE 8; Synthesis of Dextran 7OK Mono-carbonyl butanoic acid curcumin conjugate 2; Dextran 122 mg (3 x 10“3 mmol), Mono-carbonyl butanoic acid curcumin 16 mg (3Jx IO“4 mmol) and DCC (1, 3- dicyclohexylcarbodiimide) 10 mg (4.8χ lθ“4 mmol) were dissolved in 5.5 ml dry DMSO. The reaction was stirred for 24 h at reflux under argon The solution was filtered, dialyzed with SnakeSkin pleated dialysis tubing with Millipore water, centrifuged and lyophilized. The product resembled cotton candy and the yield was quantitative. NMR 1H (D2O), δ (ppm): compound 2,1.35-1.39 (m); 1.67 (m,); 1.78- 1.92 (bm); 2.33 (bm); 2.41-2.44 (t); 3.53-3.56 (t); 3.59-3.61 (m); 3.73-3.79 (m); 3.93- 4.02 (dd); 5.00 (d). Number of Curcumin molecules attached per polymer molecule is 22 (Estimated from UV spectroscopy using the extinction coefficient for Curcumin-COOH). | 100% |
Safety and Hazards
| GHS Hazard Statements | Not Classified |
Other Data
| Transportation | Under the room temperature and away from light |
| HS Code | |
| Storage | Under the room temperature and away from light |
| Shelf Life | 1 year |
| Market Price |
| Use Pattern |
| Dextran CAS#: 9004-54-0 commonly used for oil, paper and textile industries, such as photographic emulsion. |
| More Safety & Hazards From PubChem | Signal, GHS Hazard Statements, Precautionary Statement Codes, etc. |
Literature |
| Literature on PubChem | Synthesis References, Metabolite References, etc. |
Patents |
| Patents on PubChem | Related Patents Of This Product |
Transportation, Storage & Usage |
| Transportation | No Information |
| Storage | No Information |
| Usage | No Information |
Spectral Properties |
| No Information |
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