| 英文名 |
dTDP-4-dehydro-6-deoxyglucose reductase |
| Example Structure |
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| 别名 |
dTDP-4-keto-6-deoxyglucose reductase |
| EC Number |
1.1.1.266 |
| CAS编号 |
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| Comments |
The enzymes from the Gram-negative bacteria Actinobacillus actinomycetemcomitans and Escherichia coli O52 are involved in activation of fucose for incorporation into capsular polysaccharide O-antigens [1,3]. The enzyme from the Gram-positive bacterium Anoxybacillus tepidamans (Geobacillus tepidamans) is involved in activation of fucose for incorporation into the organism’s S-layer [2]. The enzyme from Escherichia coli O52 has a higher catalytic efficiency with NADH than with NADPH [3]. |
| Cofactor |
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| History |
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| Reactions |
dTDP-alpha-D-fucopyranose + NAD(P)(+) = dTDP-4-dehydro-6-deoxy-alpha-D- glucose + NAD(P)H. |
