| 英文名 |
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) |
| Example Structure |
 |
| 别名 |
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase, 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, GcpE, gcpE gene product, GcpE/IspG, IspG, IspG protein |
| EC Number |
1.17.7.1 |
| CAS编号 |
|
| Comments |
An iron-sulfur protein found in plant chloroplasts and cyanobacteria that contains a [4Fe-4S] cluster [1]. Forms part of an alternative non-mevalonate pathway for isoprenoid biosynthesis [3]. Bacteria have a similar enzyme that uses flavodoxin rather than ferredoxin (cf. EC 1.17.7.3). The enzyme from the plant Arabidopsis thaliana is active with photoreduced 5-deazaflavin but not with flavodoxin [1]. |
| Cofactor |
iron-sulfur |
| History |
|
| Reactions |
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H(2)O + 2 oxidized ferredoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + 2 reduced ferredoxin. |
