| 英文名 |
Fas-activated serine/threonine kinase |
| Example Structure |
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| 别名 |
Fas-activated serine/threonine kinase, Fas-activated serine/threonine phosphoprotein, FAST K, FASTK, FASTKD2 |
| EC Number |
2.7.11.8 |
| CAS编号 |
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| Comments |
This enzyme is activated during Fas-mediated apoptosis. Following Fas ligation, the enzyme, which is constitutively phosphorylated, is dephosphorylated, and it is the dephosphorylated form that causes phosphorylation of TIA-1, a nuclear RNA-binding protein. Phosphorylation of TIA-1 precedes the onset of DNA fragmentation. Formerly EC?2.7.1.37. |
| Cofactor |
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| History |
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| Reactions |
Atp + [Fas-activated serine/threonine protein] = adp + [Fas-activated serine/threonine phosphoprotein]. |
