| 英文名 |
formaldehyde dismutase |
| Example Structure |
 |
| 别名 |
aldehyde dismutase, cannizzanase, dismutase, formaldehyde, FDM, N,N9-dimethyl-4-nitrosoaniline oxidoreductase |
| EC Number |
1.2.98.1 |
| CAS编号 |
85204-94-0 |
| Comments |
The enzyme contains a tightly but noncovalently bound NADP(H) cofactor, as well as Zn2+ and Mg2+. Enzyme-bound NADPH formed by oxidation of formaldehyde to formate is oxidized back to NADP+ by reaction with a second formaldehyde, yielding methanol. The enzyme from the bacterium Mycobacterium sp. DSM 3803 also catalyses the reactions of EC 1.1.99.36, alcohol dehydrogenase (nicotinoprotein) and EC 1.1.99.37, methanol dehydrogenase (nicotinoprotein) [3]. Formaldehyde and acetaldehyde can act as donors; formaldehyde, acetaldehyde and propanal can act as acceptors [1,2]. |
| Cofactor |
NADP+ or NAD+;Zn2+;Mg2+ |
| History |
|
| Reactions |
2 formaldehyde + H(2)O = formate + methanol. |
