| 英文名 |
gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase |
| Example Structure |
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| 别名 |
btrG, gamma-glutamyl cyclotransferase, GGC |
| EC Number |
4.3.2.6 |
| CAS编号 |
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| Comments |
The enzyme catalyses the last step in the biosynthesis of the aminoglycoside antibiotic butirosin B. The enzyme acts as a cyclotransferase, cleaving the amide bond via transamidation using the ¦Á-amine of the terminal ¦Ã-L-glutamate of the side chain, releasing it as the cyclic 5-oxoproline. |
| Cofactor |
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| History |
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| Reactions |
Gamma-L-glutamyl-butirosin B = butirosin b + 5-oxoproline. |
