| 英文名 |
glycine/sarcosine N-methyltransferase |
| Example Structure |
 |
| 别名 |
glycine sarcosine dimethylglycine methyltransferase, glycine sarcosine methyltransferase, glycine sarcosine N-methyltransferase, GSDMT, Gsm, GsmA, GSMT, GSMT2, MXAN 7068 |
| EC Number |
2.1.1.156 |
| CAS编号 |
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| Comments |
Cells of the oxygen-evolving halotolerant cyanobacterium Aphanocthece halophytica synthesize betaine from glycine by a three-step methylation process. This is the first enzyme and it leads to the formation of either sarcosine or N,N-dimethylglycine, which is further methylated to yield betaine (N,N,N-trimethylglycine) by the action of EC 2.1.1.157, sarcosine/dimethylglycine N-methyltransferase. Differs from EC 2.1.1.20, glycine N-methyltransferase, as it can further methylate the product of the first reaction. Acetate, dimethylglycine and S-adenosyl-L-homocysteine can inhibit the reaction [3]. |
| Cofactor |
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| History |
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| Reactions |
2 S-adenosyl-L-methionine + glycine = 2 S-adenosyl-L-homocysteine + N,N-dimethylglycine. |
