| 英文名 |
heme oxygenase (biliverdin-producing, ferredoxin) |
| Example Structure |
 |
| 别名 |
ferredoxin-dependent heme oxygenase, ferredoxin-dependent soluble heme oxygenase, haem oxygenase, heme oxygenase, HO-1, HO-2, Ho1, Ho2, Ho3, HO4, HY1 |
| EC Number |
1.14.15.20 |
| CAS编号 |
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| Comments |
The enzyme, found in plants, algae, and cyanobacteria, participates in the biosynthesis of phytochromobilin and phytobilins. The terminal oxygen atoms that are incorporated into the carbonyl groups of pyrrole rings A and B of biliverdin are derived from two separate oxygen molecules. The third oxygen molecule provides the oxygen atom that converts the ¦Á-carbon to CO. Unlike this enzyme, which uses ferredoxin as its electron donor, the electron source for the related mammalian enzyme (EC 1.14.14.18) is EC 1.6.2.4, NADPH–hemoprotein reductase. |
| Cofactor |
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| History |
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| Reactions |
Protoheme + 6 reduced ferredoxin [iron-sulfur] cluster + 3 O(2) + 6 H(+) = biliverdin + Fe(2+) + Co + 6 oxidized ferredoxin [iron-sulfur] cluster + 3 H(2)O. |
