| 英文名 |
heme oxygenase (staphylobilin-producing) |
| Example Structure |
 |
| 别名 |
haem oxidase, haem oxygenase, heme oxidase, heme oxygenase, heme oxygenase (decyclizing), heme oxygenase (staphylobilin-producing) 1, heme oxygenase (staphylobilin-producing) 2, isdG, isdI |
| EC Number |
1.14.99.48 |
| CAS编号 |
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| Comments |
This enzyme, which is found in some pathogenic bacteria, is involved in an iron acquisition system that catabolizes the host’s hemoglobin. The two enzymes from the bacterium Staphylococcus aureus, encoded by the isdG and isdI genes, produce 67.5 % and 56.2 % ¦Ä-staphylobilin, respectively. |
| Cofactor |
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| History |
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| Reactions |
(1) Protoheme + 5 reduced acceptor + 4 O(2) = 5-oxo-delta-bilirubin + Fe(2+) + formaldehyde + 5 acceptor + 4 H(2)O. (2) Protoheme + 5 reduced acceptor + 4 O(2) = 15-oxo-beta-bilirubin + Fe(2+) + formaldehyde + 5 acceptor + 4 H(2)O. |
