| 英文名 |
[histone H3]-lysine36 N-dimethyltransferase |
| Example Structure |
![Example Structure of [histone H3]-lysine36 N-dimethyltransferase EC#: 2.1.1.357](/wp-content/uploads/enzyme-structure/2.1.1.357.jpg) |
| 别名 |
Ash1L, KMT3B, KMT3C, NSD2, SETMAR, Whsc1 |
| EC Number |
2.1.1.357 |
| CAS编号 |
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| Comments |
This entry describes a group of metazoan enzymes that catalyse two successive methylations of lysine36 of histone H3 (H3K36), forming mono- and dimethylated forms. These modifications influence the binding of chromatin-associated proteins. The product can be further methylated to the trimethyl form by EC 2.1.1.358, [histone H3]-dimethyl-L-lysine36 N-methyltransferase. The yeast SET2 enzyme can catalyse all three methylations (see EC 2.1.1.359, [histone H3]-lysine36 N-trimethyltransferase). |
| Cofactor |
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| History |
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| Reactions |
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