| 英文名 |
homocysteine desulfhydrase |
| Example Structure |
 |
| 别名 |
desulfhydrase, homocysteine, homocysteine desulfurase, Hyc gamma-lyase |
| EC Number |
4.4.1.2 |
| CAS编号 |
9024-41-3 |
| Comments |
A pyridoxal-phosphate protein. The enzyme cleaves a carbon-sulfur bond, releasing hydrogen sulfide and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form 2-oxobutanoate and ammonia. The latter reaction, which can occur spontaneously, can also be catalysed by EC?3.5.99.10, 2-iminobutanoate/2-iminopropanoate deaminase. |
| Cofactor |
pyridoxal 5′-phosphate |
| History |
|
| Reactions |
L-homocysteine + H(2)O = H(2)S + NH(3) + 2-oxobutanoate. |
