| 英文名 |
homospermidine synthase |
| Example Structure |
 |
| 别名 |
BvHSS, homospermidine synthase orthologue, HSPD synthase, HSS, HSS orthologue, synthase, homospermidine |
| EC Number |
2.5.1.44 |
| CAS编号 |
76106-84-8 |
| Comments |
The reaction of this enzyme occurs in three steps, with some of the intermediates presumably remaining enzyme-bound: NAD+-dependent dehydrogenation of putrescine, transfer of the 4-aminobutylidene group from dehydroputrescine to a second molecule of putrescine and reduction of the imine intermediate to form homospermidine. Hence the overall reaction is transfer of a 4-aminobutyl group. Differs from EC 2.5.1.45, homospermidine synthase (spermidine-specific), which cannot use putrescine as donor of the aminobutyl group. |
| Cofactor |
NAD+ |
| History |
|
| Reactions |
(1) 2 putrescine = sym-homospermidine + NH(3) + H(+). (2) Putrescine + spermidine = sym-homospermidine + propane-1,3-diamine. |
