| 英文名 |
inositol-polyphosphate multikinase |
| Example Structure |
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| 别名 |
1,3,4,6-tetrakisphosphate 5-kinase, 5-kinase, Arg82, ArgRIII, ARGSIII, AtIpk2a, AtIpk2b, AtIpk2beta, Impk, inositol 1,4,5-trisphosphate 3-kinase, inositol phosphate multikinase, inositol phosphate multikinase 2, inositol polyphosphate 6-/3-kinase, inositol polyphosphate kinase, inositol polyphosphate multikinase, Ins(1,4,5)P3 3-kinase, InsP4 5-kinase, IP3 3-kinase, IP3/IP4 6-/3-kinase, IP3K, IPK, Ipk2, Ipk2/Impk/IP3K, Ipk2a, Ipk2beta/IP3K, IPKII, IPMK, ITPK1, Kcs1, Kcs1p, More, phosphoinositol kinase, PI3K, StIPMK |
| EC Number |
2.7.1.151 |
| CAS编号 |
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| Comments |
This enzyme also phosphorylates Ins(1,4,5)P3?to Ins(1,3,4,5)P4, Ins(1,3,4,5)P4?to Ins(1,3,4,5,6)P5, and Ins(1,3,4,5,6)P4?to Ins(PP)P4, isomer unknown. The enzyme from the plant?Arabidopsis thaliana?can also phosphorylate Ins(1,3,4,6)P4?and Ins(1,2,3,4,6)P5?at the?D-5-position to produce 1,3,4,5,6-pentakisphosphate and inositol hexakisphosphate (InsP6), respectively [3]. Yeast produces InsP6?from Ins(1,4,5)P3?by the actions of this enzyme and EC?2.7.1.158, inositol-pentakisphosphate 2-kinase [4]. |
| Cofactor |
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| History |
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| Reactions |
2 Atp + 1D-myo-inositol 1,4,5-trisphosphate = 2 adp + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate. |
