| Comments |
This bacterial enzyme is present in pathogenic?Salmonella?species, uropathogenic and avian pathogenic?Escherichia coli?strains, and certain?Klebsiella?strains. The enzyme acts on iron(III)-bound enterobactin and?C-glucosylated derivatives known as salmochelins. Unlike EC?3.1.1.107, apo-salmochelin esterase (IroE), IroD prefers iron(III)-bound siderophores as substrates, and is assumed to act after the iron-siderophore complexes are imported into the cell. It catalyses several hydrolytic reactions, producing a mixture of iron(III)-[N-(2,3-dihydroxybenzoyl)-L-serine] complex and salmochelin SX. |
