| 英文名 |
(-)-isopiperitenone reductase |
| Example Structure |
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| 别名 |
IPR, isopiperitenone reductase, More, NADPH-dependent isopiperitenone reductase |
| EC Number |
1.3.1.82 |
| CAS编号 |
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| Comments |
The reaction occurs in the opposite direction to that shown above. The enzyme participates in the menthol-biosynthesis pathway of Mentha plants. (+)-Pulegone, (+)-cis-isopulegone and (?)-menthone are not substrates. The enzyme has a preference for NADPH as the reductant, with NADH being a poor substitute [2]. The enzyme is highly regioselective for the reduction of the endocyclic 1,2-double bond, and is stereoselective, producing only the 1R-configured product. It is a member of the short-chain dehydrogenase/reductase superfamily. |
| Cofactor |
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| History |
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| Reactions |
(+)-cis-isopulegone + NADP(+) = (-)-isopiperitenone + Nadph. |
