L-aspartate oxidase EC#: 1.4.3.16; 凯望编码 (ChemWhat Code): 1374313

英文名 L-aspartate oxidase
Example Structure Example Structure of L-aspartate oxidase EC#: 1.4.3.16
别名 AO, FIN4, L-Asp oxidase, L-aspartate oxidase, LAO, LASPO, More, nadB, oxidase, L-aspartate, StLASPO
EC Number 1.4.3.16
CAS编号 69106-47-4
Comments A flavoprotein (FAD). L-Aspartate oxidase catalyses the first step in the de novo biosynthesis of NAD+ in some bacteria. O2 can be replaced by fumarate as electron acceptor, yielding succinate [5]. The ability of the enzyme to use both O2 and fumarate in cofactor reoxidation enables it to function under both aerobic and anaerobic conditions [5]. Iminosuccinate can either be hydrolysed to form oxaloacetate and NH3 or can be used by EC 2.5.1.72, quinolinate synthase, in the production of quinolinate. The enzyme is a member of the succinate dehydrogenase/fumarate-reductase family of enzymes [5].
Cofactor FAD
History
Reactions L-aspartate + O(2) = iminosuccinate + H(2)O(2).

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