| 英文名 |
L-firefly luciferin-CoA ligase |
| Example Structure |
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| 别名 |
firefly luciferase, long-chain fattyacyl-CoA synthetase, Luc, LUC-G, LUC-H, luciferyl-CoA synthetase, protoluciferase |
| EC Number |
6.2.1.52 |
| CAS编号 |
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| Comments |
This is an alternative activity of the firefly luciferase (EC?1.13.12.7), which the enzyme exhibits under normal conditions only when acting on the?L-enantiomer of its substrate. The?D-isomer can act as a substrate for the CoA¡ªligase activity?in vitro?only under low oxygen conditions that are not found?in vivo. The activation of?L-firefly luciferin to a CoA ester is a step in a recycling pathway that results in its epimerization to the?D?enantiomer, which is the only substrate whose oxygenation results in light emission. |
| Cofactor |
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| History |
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| Reactions |
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