Lemairamin CAS#: 29946-61-0; 凯望编码 (ChemWhat Code): 1416908
Identification
| 英文名 | Lemairamin |
| 分子结构 |  |
| CAS编号 | 29946-61-0 |
| MDL Number | MFCD00610628 |
| 别名 | 2-Propenamide, N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenyl-, (2E)-;Lemairamin (WGX-50) |
| 分子式 | C19H21NO3 |
| 分子量 | 311.37 |
Physical Data
| Appearance | White powder |
| Melting Point, °C | Solvent (Melting Point) |
| 124 – 126 | |
| 132 | |
| 124.5 – 126 | acetone |
| 119 – 120 | toluene |
| 122 – 124 | acetone, hexane |
| 127 | aq. ethanol |
Spectra
| Description (NMR Spectroscopy) | Nucleus (NMR Spectroscopy) | Solvents (NMR Spectroscopy) | Temperature (NMR Spectroscopy), °C | Frequency (NMR Spectroscopy), MHz |
| Chemical shifts | 1H | chloroform-d1 | 500 | |
| Chemical shifts | 13C | chloroform-d1 | 125 | |
| Chemical shifts | 1H | dimethylsulfoxide-d6 | 300 | |
| Chemical shifts, Spectrum | 1H | chloroform-d1 | 300 | |
| Chemical shifts, Spectrum | 13C | chloroform-d1 | 24.84 | 125 |
| Description (IR Spectroscopy) | Solvent (IR Spectroscopy) |
| Bands | neat (no solvent, solid phase) |
| Bands | KBr |
| Description (UV/VIS Spectroscopy) | Solvent (UV/VIS Spectroscopy) | Comment (UV/VIS Spectroscopy) | Absorption Maxima (UV/VIS), nm | Ext./Abs. Coefficient, l·mol-1cm-1 |
| Absorption maxima | methanol | 206, 277 |
Route of Synthesis (ROS)
Route of Synthesis (ROS) of Lemairamin CAS 29946-61-0
| Conditions | Yield |
| With sodium hydroxide In dichloromethane at 20℃; for 3h; Schotten-Baumann Reaction; | 91% |
| With sodium hydroxide In dichloromethane; water at 20℃; for 3h; Schotten-Baumann Reaction; | 91% |
| Experimental Procedure An amount of 458mg of cinnamoyl chloride (2.76mmol) dissolved in CH2Cl2 (1mL) was added dropwise at 0°C to a solution of 2-(3,4-dimethoxyphenyl)ethylamine (500mg, 2.76mmol) in CH2Cl2 (20mL) and 5% aqueous NaOH (4.4mL) with stirring at room temperature for 3h. Then, the mixture was stirred with 2.5% aqueous HCl. The organic solution was washed with brine (2×10ml) and H2O (2×10ml), dried over anhydrous Na2SO4 and evaporated to dryness. The residue obtained was purified by silica gel column chromatography (Hexane/CH2Cl2/EtOAc, 20:70:10) to afford the acetamide 1 (781mg, 91%) as a white oil. 1H NMR (500MHz, CDCl3): δ=7.62 (d, J=15.6Hz, 1H, CH-β). |
Safety and Hazards
No data available
Other Data
| Transportation | Under room temperature and away from light |
| HS Code | |
| Storage | Under the room temperature and away from light |
| Shelf Life | 2 years |
| Market Price |
| Toxicity/Safety Pharmacology |
| Quantitative Results |
| Use Pattern |
| Lemairamin CAS#: 29946-61-0 used as the next generation of anti-aging material. And Lemairamin has some applications in the medical field, primarily due to its effects on the nervous system. |
试剂采购 | |
| 没有试剂厂商? | 向凯望发送快速询价 |
| 想要被列为试剂厂商? (付费服务) | 点击这里联系凯望 |
认证生产商 | |
| 想要被列为认证生产商 (需要通过认证)? | 请下载并填写 这份表格并发邮件到approved-manufacturers@chemwhat.com |
其他供应商 | |
| Watson International Limited | 访问Watson官网 |
如需其他帮助，请联系我们 | |
| 联系我们获取其它信息或服务 | 点击这里联系凯望 |