| 英文名 |
lipid-phosphate phosphatase |
| Example Structure |
 |
| 别名 |
EPXH2, lipid phosphatase, lipid phosphate phosphatase, More, Nterm-phos, soluble epoxide hydrolase |
| EC Number |
3.1.3.76 |
| CAS编号 |
|
| Comments |
Requires Mg2+?for maximal activity. The enzyme from mammals is a bifunctional enzyme: the N-terminal domain exhibits lipid-phosphate-phosphatase activity and the C-terminal domain has the activity of EC?3.3.2.10, soluble epoxide hydrolase (sEH) [1]. The best substrates for this enzyme are 10-hydroxy-9-(phosphonooxy)octadecanoates, with the?threo- form being a better substrate than the?erythro- form [1]. The phosphatase activity is not found in plant sEH or in EC?3.3.2.9, microsomal epoxide hydrolase, from mammals [1]. |
| Cofactor |
Mg2+ |
| History |
|
| Reactions |
(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H(2)O = (9S,10S)- 9,10-dihydroxyoctadecanoate + phosphate. |
