lipoate-protein ligase EC#: 6.3.1.20 • ChemWhat中文网

lipoate-protein ligase EC#: 6.3.1.20; 凯望编码 (ChemWhat Code): 1383705


认证生产商
想要被列为认证生产商 (需要通过认证)?	请下载并填写这份表格并发邮件到approved-manufacturers@chemwhat.com


其他供应商
Watson International Limited	访问Watson官网

英文名	lipoate-protein ligase
Example Structure
别名	CTD, LIP3, LipB, LipL1, lipoate ligase, lipoate ligase like protein, lipoate protein ligase, lipoate protein ligase B, lipoate-bound lipoate ligase 1, lipoate-protein ligase, lipoate-protein ligase A, lipoic acid ligase, lipoic acid ligase A, lipoic acid protein ligase, lipoic acid protein ligase A1, lipoyl ligase, lipoyl-protein ligase A, LPLA, LplA-LplB complex, LplA1, LplA1Ct, Lpla2, LplB, Oryza s. lipoate-protein ligase A, OsLPLA, PfLipL1
EC Number	6.3.1.20
CAS编号
Comments	Requires Mg2+. This enzyme participates in lipoate salvage, and is responsible for lipoylation in the presence of exogenous lipoic acid [7]. The enzyme attaches lipoic acid to the lipoyl domains of certain key enzymes involved in oxidative metabolism, including pyruvate dehydrogenase (E2?domain), 2-oxoglutarate dehydrogenase (E2?domain), the branched-chain 2-oxoacid dehydrogenases and the glycine cleavage system (H protein) [6]. Lipoylation is essential for the function of these enzymes. The enzyme can also use octanoate instead of lipoate.
Cofactor	Mg2+
History
Reactions	Atp + (R)-lipoate + a [lipoyl-carrier protein]-L-lysine = a [lipoyl- carrier protein]-N(6)-(lipoyl)lysine + Amp + diphosphate.