| 英文名 |
malonyl-S-ACP:biotin-protein carboxyltransferase |
| Example Structure |
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| 别名 |
acetyl-S-acyl carrier protein:malonate acyl carrier protein-SH transferase, MadC,D, malonyl-S-acyl-carrier protein:biotin-protein carboxyltransferase, malonyl-[acyl-carrier protein]:biotinyl-[protein] carboxyltransferase |
| EC Number |
2.1.3.10 |
| CAS编号 |
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| Comments |
Derived from the components MadC and MadD of the anaerobic bacterium Malonomonas rubra, this enzyme is a component of EC 7.2.4.4, biotin-dependent malonate decarboxylase. The carboxy group is transferred from malonate to the prosthetic group of the biotin protein (MadF) with retention of configuration [2]. Similar to EC 4.1.1.87, malonyl-S-ACP decarboxylase, which forms part of the biotin-independent malonate decarboxylase (EC 4.1.1.88), this enzyme also follows on from EC 2.3.1.187, acetyl-S-ACP:malonate ACP transferase, and results in the regeneration of the acetyl-[acyl-carrier protein] [3]. |
| Cofactor |
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| History |
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| Reactions |
A malonyl-[acyl-carrier protein] + a biotinyl-[protein] = an acetyl- [acyl-carrier protein] + a carboxybiotinyl-[protein]. |
