methylecgonone reductase EC#: 1.1.1.334; 凯望编码 (ChemWhat Code): 1373449

英文名 methylecgonone reductase
Example Structure Example Structure of methylecgonone reductase EC#: 1.1.1.334
别名
EC Number 1.1.1.334
CAS编号
Comments The enzyme from the plant Erythroxylum coca catalyses the penultimate step in the biosynthesis of cocaine. In vivo the reaction proceeds in the opposite direction. With NADH instead of NADPH the reaction rate is reduced to 14%. The enzyme also reduces tropinone, nortropinone and 6-hydroxytropinone but with lower reaction rates.
Cofactor
History
Reactions Ecgonine methyl ester + NADP(+) = ecgonone methyl ester + Nadph.

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