| 英文名 |
methylenetetrahydrofolate reductase (ferredoxin) |
| Example Structure |
 |
| 别名 |
5,10-methylenetetrahydrofolate reductase, metF, methylene-H4F reductase, methylenetetrahydrofolate reductase |
| EC Number |
1.5.7.1 |
| CAS编号 |
|
| Comments |
An iron-sulfur flavoprotein that also contains zinc. The enzyme from Clostridium formicoaceticum catalyses the reduction of methylene blue, menadione, benzyl viologen, rubredoxin or FAD with 5-methyltetrahydrofolate and the oxidation of reduced ferredoxin or FADH2 with 5,10-methylenetetrahydrofolate. However, unlike EC 1.5.1.20, methylenetetrahydrofolate reductase [NAD(P)H], there is no activity with NAD(P)H. |
| Cofactor |
iron-sulfur;Zn2+;flavoprotein |
| History |
|
| Reactions |
5-methyltetrahydrofolate + 2 oxidized ferredoxin = 5,10- methylenetetrahydrofolate + 2 reduced ferredoxin + 2 H(+). |
