| 英文名 |
Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase |
| Example Structure |
 |
| 别名 |
ADPRibase-I, ADPRibase-II, ADPRibase-Mn, Adprm, Mn(2+)-dependent ADP-ribose/CDP-alcohol pyrophosphatase, Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase |
| EC Number |
3.6.1.53 |
| CAS编号 |
|
| Comments |
Requires Mn2+, which cannot be replaced by Mg2+, for activity. ADP-D-ribose, CDP-choline, CDP-ethanolamine and ADP are substrates for this enzyme but ADP-D-glucose, UDP-D-glucose, CDP-D-glucose, CDP, CMP and AMP are not hydrolysed [2]. In rat, the enzyme is found predominantly in thymus and spleen. |
| Cofactor |
Mn2+ |
| History |
|
| Reactions |
(1) CDP-choline + H(2)O = Cmp + phosphocholine. (2) ADP-D-ribose + H(2)O = Amp + D-ribose 5-phosphate. |
