| 英文名 |
mRNA(cytosine6666) deaminase |
| Example Structure |
 |
| 别名 |
apo B messenger RNA editing protein, apoB mRNA-editing enzyme catalytic polypeptide 1, APOBEC-1, APOBEC1, apolipoprotein B mRNA editing enzyme, apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1, REPR |
| EC Number |
3.5.4.36 |
| CAS编号 |
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| Comments |
The apolipoprotein B mRNA editing enzyme complex catalyses the editing of apolipoprotein B mRNA at cytidine6666?to uridine, thereby transforming the codon for glutamine-2153 to a termination codon. Editing results in translation of a truncated apolipoprotein B isoform (apoB-48) with distinct functions in lipid transport. The catalytic component (APOBEC-1) contains zinc at the active site [3]. |
| Cofactor |
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| History |
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| Reactions |
Cytosine(6666) in apolipoprotein B mRNA + H(2)O = uracil(6666) in apolipoprotein B mRNA + NH(3). |
