| 英文名 |
mycothiol synthase |
| Example Structure |
 |
| 别名 |
MSH acetyltransferase, MSH synthase, MshD, nshD |
| EC Number |
2.3.1.189 |
| CAS编号 |
|
| Comments |
This enzyme catalyses the last step in the biosynthesis of mycothiol, the major thiol in most actinomycetes, including Mycobacterium [1]. The enzyme is a member of a large family of GCN5-related N-acetyltransferases (GNATs) [2]. The enzyme has been purified from Mycobacterium tuberculosis H37Rv. Acetyl-CoA is the preferred CoA thioester but propionyl-CoA is also a substrate [3]. |
| Cofactor |
|
| History |
|
| Reactions |
Desacetylmycothiol + acetyl-CoA = CoA + mycothiol. |
