| 英文名 |
N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase |
| Example Structure |
 |
| 别名 |
cell wall rhamnosyltransferase, Cj1125c, dTDP-Rha:alpha-D-GlcNAc-pyrophosphate polyprenol, alpha-3-L-rhamnosyltransferase, lmo1080, PglA, RmlT, WbbL |
| EC Number |
2.4.1.289 |
| CAS编号 |
|
| Comments |
Requires Mn2+ or Mg2+. Isolated from Mycobacterium smegmatis [1] and Mycobacterium tuberculosis [2]. The enzyme catalyses the addition of a rhamnosyl unit to N-acetyl-¦Á-D-glucosaminyl-diphospho-trans,octacis-decaprenol, completing the synthesis of the linkage unit that attaches the arabinogalactan moiety to the peptidoglycan moiety in Mycobacterial cell wall. |
| Cofactor |
Mn2+ or Mg2+ |
| History |
|
| Reactions |
dTDP-6-deoxy-beta-L-mannose + N-acetyl-alpha-D-glucosaminyl-diphospho- trans,octacis-decaprenol = dTDP + alpha-L-rhamnopyranosyl-(1->3)-N- acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol. |
